| Qlik | King of Prussia | 1993 |
| Qualcomm | San Diego | julho 1985 |
| Qualtrics | Provo | 2002 |
| QVC | Düsseldorf | 1986 |
| Radisson Hotel Group | Minnetonka | 1962 |
| Rainforest Cafe | Houston | 1994 |
| Raising Cane's Chicken Fingers | Baton Rouge | 1996 |
| Ralph Lauren (marca) | Nova Iorque | 1967 |
| Rambus | Sunnyvale | 1990 |
| Real3D | Orlando | 1986 |
| RealNetworks | Seattle | 1993 |
| Red Ventures | Charlotte, Fort Mill, Indian Land | 2000 |
| Redback Networks | São José | 1996 |
| Reebok | Boston | 1895 |
| Regent Seven Seas Cruises | Miami | 1990 |
| Remington Rand | Buffalo, Nova Iorque | 1927 |
| Remo | Santa Clarita | 1957 |
| Remote Control Productions | Santa Mônica | 1989 |
| Renaissance Technologies | Setauket-East Setauket | 1982 |
| RhythmOne | São Francisco | 2004 |
| Rite Aid | Filadélfia, East Pennsboro Township | 1962 |
| Rivian | Detroit | junho 2009 |
| Robinson Helicopter | Zamperini Field | 1973 |
| Rocketdyne | Canoga Park | 2005 |
| Rogers Locomotive and Machine Works | — | 1832 |
| Rohm and Haas | Filadélfia | 1 de setembro de 1909 |
| Roku | Los Gatos | outubro 2002 |
| Rotten Tomatoes | São Francisco | 19 de agosto de 1998 |
| Rough Draft Studios | Glendale | 1990 |
| Roxio | Santa Clara | 2001 |
| RR Donnelley | Chicago | 1864 |
| RTX | condado de Arlington | 3 de abril de 2020 |
| Ryder | Coral Gables | 1933 |
| S&P Global | Rockefeller Center, Nova Iorque | — |
| S3 Graphics | Fremont, Califórnia | janeiro 1989 |
| Saatchi & Saatchi | Nova Iorque | 1970 |
| SAE International | Warrendale | 1905 |
| Safeway | Pleasanton | 1915 |
| Saks Fifth Avenue | Nova Iorque | 1898 |
| San Diego Studios | San Diego | 2001 |
| Sanmina-SCI | São José | 1980 |
| Schecter Guitar Research | Los Angeles | 1976 |
| Schweizer Aircraft Corporation | Horseheads, Nova Iorque | 1939 |
| Schwinn | Chicago | 1895 |
| Sears | Hoffman Estates | 1892 |
| Sears Holdings Corporation | Hoffman Estates | 2005 |
| Seattle's Best Coffee | Seattle | 1991 |
| Seeburg Corporation | Chicago | 1902 |