| Ralph Lauren (marca) | Nova Iorque | 1967 |
| Rambus | Sunnyvale | 1990 |
| RealNetworks | Seattle | 1993 |
| Reebok | Boston | 1895 |
| Remo | Santa Clarita | 1957 |
| Remote Control Productions | Santa Mônica | 1989 |
| Rite Aid | Filadélfia, East Pennsboro Township | 1962 |
| Rivian | Detroit | junho 2009 |
| Robinson Helicopter | Zamperini Field | 1973 |
| Rohm and Haas | Filadélfia | 1 de setembro de 1909 |
| Roku | Los Gatos | outubro 2002 |
| Ross Stores | Dublin | 1954 |
| Rough Draft Studios | Glendale | 1990 |
| S&P Global | Rockefeller Center, Nova Iorque | — |
| Safeway | Pleasanton | 1915 |
| Schecter Guitar Research | Los Angeles | 1976 |
| Sears Holdings Corporation | Hoffman Estates | 2005 |
| Sherwin-Williams | Cleveland | 1866 |
| Shimmer Women Athletes | Illinois, Chicago, Berwyn | 6 de novembro de 2005 |
| Shure | Niles | 1925 |
| Siebel Systems | Austin | 1993 |
| Sigma-Aldrich | St. Louis | 1976 |
| Silicon Graphics | Sunnyvale, Mountain View | 9 de novembro de 1981 |
| Sinclair Broadcast Group | Hunt Valley, Cockeysville, Union Valley | 1971 |
| Skechers | Manhattan Beach | 1992 |
| Smithfield Foods | Smithfield | 1936 |
| Southern Company | Atlanta | 1945 |
| Spanx | Atlanta | 2000 |
| Specialized | Morgan Hill | 1974 |
| Splunk Inc. | São Francisco | 2004 |
| Sprint Nextel | Overland Park | 1899 |
| State Street Corporation | Boston | 1792 |
| Stellantis North America | Chrysler Headquarters and Technology Center | 28 de abril de 2009 |
| Storage Technology Corporation | Louisville | 1969 |
| Strategic Simulations | Sunnyvale | 1979 |
| Substack | — | 29 de novembro de 2017 |
| Subway | Milford | 28 de agosto de 1965 |
| Sumisho Air Lease | Los Angeles | 2010 |
| Sunkist Growers | Los Angeles | 29 de agosto de 1893 |
| Sunoco | Dallas | 1886 |
| Supreme | Nova Iorque | abril 1994 |
| Sylvania Electric Products | — | 1942 |
| Taser International | Scottsdale | setembro 1993 |
| TD Ameritrade | Omaha | 1971 |
| Tenneco | Lake Forest | 1930 |
| Tesla | Austin | 1 de julho de 2003 |
| Tesoro Corporation | — | 1968 |
| The Bank of New York Mellon | Nova Iorque | 2007 |